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Madness and Memory : The Discovery of Prions--A New Biological Principle of Disease download ebook

Stanley B. Prusiner: Madness and Memory : The Discovery of Prions--A New Biological Principle of Disease

Madness and Memory : The Discovery of Prions--A New Biological Principle of Disease


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A first-person account of a revolutionary scientific discovery that is now helping to unravel the mysteries of brain diseases In 1997, Stanley B. Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate. His struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement. In this book, Prusiner tells the remarkable story of his discovery of prions-infectious proteins that replicate and cause disease but surprisingly contain no genetic material-and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner's hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer's, Parkinson's, Lou Gehrig's and other devastating diseases of the brain?

Two men have been enlisted to kill the head of the Gestapo. This is Operation Anthropoid, Prague, 1942: two Czechoslovakian parachutists sent on a daring mission by London to assassinate Reinhard Heydrich - chief of the Nazi secret services, 'the hangman of Prague', 'the blond beast', 'the most dangerous man in the Third Reich'. His boss is Heinrich Himmler but Madness and Memory : The Discovery of Prions--A New Biological Principle of Disease free pdf everyone in the SS says 'Himmler's brain is called Heydrich', which in German spells "HHhH". All the characters in "HHhH" are real. All the events depicted are true. But alongside the nerve-shredding preparations for the attack runs another story: when you are a novelist writing about real people, how do you resist the temptation to make things up? "HHhH" is a panorama of the Third Reich told through the life of one outstandingly brutal man, a story of unbearable heroism and loyalty, revenge and betrayal. It is improbably entertaining and electrifyingly modern, a moving and shattering work of fiction.


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Author: Stanley B. Prusiner
Number of Pages: 344 pages
Published Date: 26 Jan 2016
Publisher: Yale University Press
Publication Country: New Haven, United States
Language: English
ISBN: 9780300216905
Download Link: Click Here
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